NADH:ubiquinone Oxidoreductase Subunit S4 (NDUFS4) Antibody

NDUFS4 is an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), or NADH:ubiquinone oxidoreductase, the first multi-subunit enzyme complex of the mitochondrial respiratory chain. Complex I plays a vital role in cellular ATP production, the primary source of energy for many crucial processes in living cells. It removes electrons from NADH and passes them by a series of different protein-coupled redox centers to the electron acceptor ubiquinone. In well-coupled mitochondria, the electron flux leads to ATP generation via the building of a proton gradient across the inner membrane.

Target	NADH:ubiquinone Oxidoreductase Subunit S4 (NDUFS4)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, WB, IHC, FCM
Host	Rabbit
Recommended dilutions	WB: 1/2000, IHC-P: 1/250, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 131-160 amino acids from the C-terminal region of human NDUFS4.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O43181 (UniProt, ExPASy)
UniProt Secondary AC	Q9BS69
UniProt Entry Name	NDUS4_HUMAN
Gene Symbol	NDUFS4
KEGG	hsa:4724
String	9606.ENSP00000296684
Molecular Weight	Calculated MW: 20.1 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on NADH:ubiquinone Oxidoreductase Subunit S4 (NDUFS4)

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