NADH:ubiquinone Oxidoreductase Subunit S4 (NDUFS4) Antibody

NDUFS4 Antibody is a Rabbit Polyclonal antibody against NDUFS4. This gene encodes an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), or NADH:ubiquinone oxidoreductase, the first multi-subunit enzyme complex of the mitochondrial respiratory chain. Complex I plays a vital role in cellular ATP production, the primary source of energy for many crucial processes in living cells. It removes electrons from NADH and passes them by a series of different protein-coupled redox centers to the electron acceptor ubiquinone. In well-coupled mitochondria, the electron flux leads to ATP generation via the building of a proton gradient across the inner membrane. Complex I is composed of at least 41 subunits, of which 7 are encoded by the mitochondrial genome and the remainder by nuclear genes.

Target	NADH:ubiquinone Oxidoreductase Subunit S4 (NDUFS4)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/100 - 1/500, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-175 of human NDUFS4.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O43181 (UniProt, ExPASy)
UniProt Secondary AC	Q9BS69
UniProt Entry Name	NDUS4_HUMAN
Gene Symbol	NDUFS4
GeneID	4724
NCBI Accession	NP_002486.1
KEGG	hsa:4724
String	9606.ENSP00000296684
Molecular Weight	Calculated MW: 20 kDa Observed MW: 18 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on NADH:ubiquinone Oxidoreductase Subunit S4 (NDUFS4)

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