Neurofilament, Light Polypeptide (NEFL) Antibody

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Catalogue No: abx011248
Price: US$420.50
(Size: 100 µl)

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Datasheet SDS
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.

Target Neurofilament, Light Polypeptide (NEFL)
Clonality Monoclonal
Reactivity Human
Tested Applications ELISA, WB, IHC, IF/ICC, FCM
Host Mouse
Recommended dilutions ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Purified recombinant fragment of human NEFL expressed in E. coli.
Isotype IgG1
Form Liquid
Purification Unpurified ascites.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P07196 (UniProt, ExPASy)
UniProt Secondary AC B9ZVN2, Q16154, Q8IU72
UniProt Entry Name NFL_HUMAN
Gene Symbol NEFL
GeneID 4747
OMIM 162280
HGNC 7739
KEGG hsa:4747
Ensembl ENSG00000277586
String 9606.ENSP00000482169
Molecular Weight 62 kDa
Buffer Ascitic fluid containing 0.03% sodium azide.
Concentration Not determined.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Neurofilament, Light Polypeptide (NEFL)


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