NIMA Related Kinase 3 (NEK3) Antibody

In Aspergillus nidulans, lack of the serine/threonine kinase NimA (never in mitosis A) results in cell cycle arrest in G2, while overexpression causes the premature onset of mitotic events. NEK3 is similar in sequence to the Aspergillus nidulans protein and may therefore play a role in mitotic regulation. However, the encoded protein differs from other NimA family members in that it is not cell cycle regulated and is found primarily in the cytoplasm.

Target	NIMA Related Kinase 3 (NEK3)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 331-361 amino acids from the Central region of human NEK3.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P51956 (UniProt, ExPASy)
UniProt Secondary AC	A8K2J4, Q5TAP2, Q8J023, Q8WUN5
UniProt Entry Name	NEK3_HUMAN
NCBI Accession	NP_001139571.1 NP_002489.1 NP_689933.1
KEGG	hsa:4752
String	9606.ENSP00000484443
Molecular Weight	Calculated MW: 57.7 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on NIMA Related Kinase 3 (NEK3)

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