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NIMA Related Kinase 3 (NEK3) Antibody
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Catalogue No: abx005111
Price:
US$203.00
(Size: 20 µl)
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NEK3 Antibody is a Rabbit Polyclonal antibody against NEK3. This gene encodes a member of the NimA (never in mitosis A) family of serine/threonine protein kinases. The encoded protein differs from other NimA family members in that it is not cell cycle regulated and is found primarily in the cytoplasm. The kinase is activated by prolactin stimulation, leading to phosphorylation of VAV2 guanine nucleotide exchange factor, paxillin, and activation of the RAC1 GTPase. Multiple transcript variants encoding different isoforms have been found for this gene.
Research Articles on NIMA Related Kinase 3 (NEK3)
| Target | NIMA Related Kinase 3 (NEK3) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 267-506 of human NEK3. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P51956 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K2J4, Q5TAP2, Q8J023, Q8WUN5 |
| UniProt Entry Name | NEK3_HUMAN |
| Gene Symbol | NEK3 |
| GeneID | 4752 |
| NCBI Accession | NP_689933.1 |
| KEGG | hsa:4752 |
| String | 9606.ENSP00000484443 |
| Molecular Weight | Calculated MW: 58 kDa Observed MW: 55 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |