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Neurogenic Differentiation Factor 1 (NEUROD1) Antibody
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Catalogue No: abx031452
Price:
US$326.25
(Size: 80 µl)
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NeuroD1 is a transcriptional activator that acts as a differentiation factor during neurogenesis. It has been demonstrated to bind to the insulin gene E-box. Efficient DNA binding requires dimerization with another basic helix-loop-helix (bHLH) protein. Defects in NEUROD1 are a cause of maturity onset diabetes of the young type VI (MODY6). MODY6 is a form of non-insulin-dependent diabetes mellitus characterized by an autosomal dominant mode of inheritance, onset during young adulthood and a primary defect in insulin secretion.
Research Articles on Neurogenic Differentiation Factor 1 (NEUROD1)
| Target | Neurogenic Differentiation Factor 1 (NEUROD1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 318-348 amino acids from the C-terminal region of human NeuroD1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q13562 (UniProt, ExPASy) |
| UniProt Entry Name | NDF1_HUMAN |
| NCBI Accession | NP_002491.2 |
| KEGG | hsa:4760 |
| String | 9606.ENSP00000295108 |
| Molecular Weight | Calculated MW: 39.9 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |