+44 (0) 1223 755950
+1 832 327 7413
NFKB1 (pS932) Antibody
REQUEST MORE INFO
Catalogue No: abx000464
Price:
US$551.00
(Size: 100 µl)
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
NFKB1 (pS932) Antibody is a Rabbit Polyclonal antibody against NFKB1 (pS932). This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene.
Research Articles on NFKB1 (pS932)
| Target | NFKB1 (pS932) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A phospho specific peptide corresponding to residues surrounding S932 of human NFKB1 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P19838 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K5Y5, B3KVE8, Q68D84, Q86V43, Q8N4X7, Q9NZC0 |
| UniProt Entry Name | NFKB1_HUMAN |
| Gene Symbol | NFKB1 |
| GeneID | 4790 |
| KEGG | hsa:4790 |
| String | 9606.ENSP00000226574 |
| Molecular Weight | Calculated MW: 105 kDa Observed MW: 105 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |