Nuclear Transcription Factor Y Subunit Beta (NFYB) Antibody

The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit B, forms a tight dimer with the C subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence; protein sequence alignments and experiments with mutants.

Target	Nuclear Transcription Factor Y Subunit Beta (NFYB)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IF/ICC: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 17-46 amino acids from the N-terminal region of human NFYB.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P25208 (UniProt, ExPASy)
UniProt Secondary AC	A8K7B9, Q96IY8
UniProt Entry Name	NFYB_HUMAN
Gene Symbol	NFYB
KEGG	hsa:4801
String	9606.ENSP00000240055
Molecular Weight	Calculated MW: 22.8 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse, Rat, Cow, Chicken and Horse NFYB.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Nuclear Transcription Factor Y Subunit Beta (NFYB)

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