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E3 Ubiquitin-Protein Ligase NHLRC1 (NHLRC1) Antibody
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Catalogue No: abx005115
Price:
US$217.50
(Size: 20 µl)
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NHLRC1 Antibody is a Rabbit Polyclonal antibody against NHLRC1. The protein encoded by this gene is a single subunit E3 ubiquitin ligase. Laforin is polyubiquitinated by the encoded protein. Defects in this intronless gene lead to an accumulation of laforin and onset of Lafora disease, also known as progressive myoclonic epilepsy type 2 (EPM2).
Research Articles on E3 Ubiquitin-Protein Ligase NHLRC1 (NHLRC1)
| Target | E3 Ubiquitin-Protein Ligase NHLRC1 (NHLRC1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/2000 - 1/7000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human NHLRC1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q6VVB1 (UniProt, ExPASy) |
| UniProt Secondary AC | Q3SYB1, Q5VUK7, Q6IMH1 |
| UniProt Entry Name | NHLC1_HUMAN |
| Gene Symbol | NHLRC1 |
| GeneID | 378884 |
| NCBI Accession | NP_940988.2 |
| KEGG | hsa:378884 |
| String | 9606.ENSP00000345464 |
| Molecular Weight | Calculated MW: 42 kDa Observed MW: 42/45 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |