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NFKB Inhibitor Interacting Ras Like 1 (NKIRAS1) Antibody
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Catalogue No: abx029543
Price:
US$290.00
(Size: 80 µl)
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Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP-and GDP-bound forms block phosphorylation of NFKBIB.
Research Articles on NFKB Inhibitor Interacting Ras Like 1 (NKIRAS1)
| Target | NFKB Inhibitor Interacting Ras Like 1 (NKIRAS1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 48-76 amino acids from the Central region of human NKIRAS1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9NYS0 (UniProt, ExPASy) |
| UniProt Secondary AC | Q96K18 |
| UniProt Entry Name | KBRS1_HUMAN |
| Gene Symbol | NKIRAS1 |
| String | 9606.ENSP00000393785 |
| Molecular Weight | Calculated MW: 21.6 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Monkey NKIRAS1. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |