NK2 Homeobox 5 (NKX2-5) Antibody

This gene encodes a homeobox-containing transcription factor. This transcription factor functions in heart formation and development. Mutations in this gene cause atrial septal defect with atrioventricular conduction defect, and also tetralogy of Fallot, which are both heart malformation diseases. Mutations in this gene can also cause congenital hypothyroidism non-goitrous type 5, a non-autoimmune condition. Alternative splicing results in multiple transcript variants.

Target	NK2 Homeobox 5 (NKX2-5)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 82-111 amino acids from the Central region of human NKX2-5.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P52952 (UniProt, ExPASy)
UniProt Secondary AC	A8K3K0, B4DNB6, E9PBU6
UniProt Entry Name	NKX25_HUMAN
KEGG	hsa:1482
String	9606.ENSP00000327758
Molecular Weight	Calculated MW: 34.9 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on NK2 Homeobox 5 (NKX2-5)

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