NK3 Homeobox 1 (NKX3-1) Antibody

NKX3-1 is a transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. It play an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. It Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells.

Target	NK3 Homeobox 1 (NKX3-1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC, FCM
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 118-145 amino acids from the Central region of human NKX3-1.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q99801 (UniProt, ExPASy)
UniProt Secondary AC	O15465, Q9H2P4, Q9H2P5, Q9H2P6, Q9H2P7, Q9HBG0
UniProt Entry Name	NKX31_HUMAN
Gene Symbol	NKX3-1
KEGG	hsa:4824
String	9606.ENSP00000370253
Molecular Weight	Calculated MW: 26.4 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse NKX3-1.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on NK3 Homeobox 1 (NKX3-1)

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