+44 (0) 1223 755950
+1 832 327 7413
orders@abbexa.com
Help us improve!
How easy was it for you
to use the website?
to use the website?
How can we improve?
Submit
Sales & Advice:
UK +44 (0) 1223 755950 US +1 832 327 7413 @
NLR Family Pyrin Domain Containing 10 (NLRP10) Antibody
REQUEST MORE INFO
Catalogue No: abx027423
Price:
US$326.25
(Size: 80 µl)
Click on the image to see the image legend
Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis. [provided by RefSeq].
Research Articles on NLR Family Pyrin Domain Containing 10 (NLRP10)
| Target | NLR Family Pyrin Domain Containing 10 (NLRP10) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 466-494 amino acids from the C-terminal region of human NLRP10. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q86W26 (UniProt, ExPASy) |
| UniProt Secondary AC | Q2M3C4, Q6JGT0 |
| UniProt Entry Name | NAL10_HUMAN |
| Gene Symbol | NLRP10 |
| KEGG | hsa:338322 |
| String | 9606.ENSP00000327763 |
| Molecular Weight | Calculated MW: 75 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |