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NACHT, LRR And PYD Domains-Containing Protein 12 (NLRP12) Antibody
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Catalogue No: abx025261
Price:
US$326.25
(Size: 80 µl)
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This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Alternatively spliced transcript variants encoding distinct isoforms have been described but the full-length nature of some of these has not been determined.
Research Articles on NACHT, LRR And PYD Domains-Containing Protein 12 (NLRP12)
| Target | NACHT, LRR And PYD Domains-Containing Protein 12 (NLRP12) |
| Clonality | Monoclonal |
| Reactivity | Mouse |
| Tested Applications | ELISA, WB |
| Host | Mouse |
| Recommended dilutions | WB: 1/500 - 1/1500. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Human NLRP12 recombinant protein. |
| Isotype | IgM Kappa |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P59046 (UniProt, ExPASy) |
| UniProt Secondary AC | A8MTQ2, B3KTE7, Q8NEU4, Q9BY26 |
| UniProt Entry Name | NAL12_HUMAN |
| Gene Symbol | NLRP12 |
| GeneID | 91662 |
| HGNC | 22938 |
| KEGG | hsa:91662 |
| String | 9606.ENSP00000375653 |
| Molecular Weight | Calculated MW: 120 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |