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NLR Family Pyrin Domain Containing 4 (NLRP4) Antibody
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Catalogue No: abx030525
Price:
US$290.00
(Size: 80 µl)
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NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP4, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 [PubMed 12563287]).
Research Articles on NLR Family Pyrin Domain Containing 4 (NLRP4)
| Target | NLR Family Pyrin Domain Containing 4 (NLRP4) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 121-149 amino acids from the N-terminal region of human NLRP4. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q96MN2 (UniProt, ExPASy) |
| UniProt Secondary AC | Q86W87, Q96AY6 |
| UniProt Entry Name | NALP4_HUMAN |
| Gene Symbol | NLRP4 |
| KEGG | hsa:147945 |
| String | 9606.ENSP00000301295 |
| Molecular Weight | Calculated MW: 113 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |