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NMD3 Ribosome Export Adaptor (NMD3) Antibody
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Catalogue No: abx031045
Price:
US$326.25
(Size: 80 µl)
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It has been suggested that NMD3 is a cytoplasmic factor required for a late cytoplasmic assembly step of the 60S subunit but is not a ribosomal protein. A mutation in NMD3 was found to be lethal in the absence of XRN1, which encodes the major cytoplasmic exoribonuclease responsible for mRNA turnover. The NMD3 protein sequence does not contain readily recognizable motifs of known function. However, NMD3 orthologues display an amino-terminal domain containing four repeats of Cx2C, reminiscent of zinc-binding proteins, implicated in nucleic acid binding or protein oligomerization.
Research Articles on NMD3 Ribosome Export Adaptor (NMD3)
| Target | NMD3 Ribosome Export Adaptor (NMD3) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 410-440 amino acids from the C-terminal region of human NMD3. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q96D46 (UniProt, ExPASy) |
| UniProt Secondary AC | D3DNM7, Q9Y2Z6 |
| UniProt Entry Name | NMD3_HUMAN |
| KEGG | hsa:51068 |
| String | 9606.ENSP00000419004 |
| Molecular Weight | Calculated MW: 57.6 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |