RNA-Binding Protein NOB1 (NOB1) Antibody

RNA-Binding Protein NOB1 (NOB1) Antibody is a Mouse Monoclonal against RNA-Binding Protein NOB1 (NOB1). In yeast, over 200 protein and RNA cofactors are required for ribosome assembly, and these are generally conserved in eukaryotes. These factors orchestrate modification and cleavage of the initial 35S precursor rRNA transcript into the mature 18S, 5.8S, and 25S rRNAs, folding of the rRNA, and binding of ribosomal proteins and 5S RNA. Nob1 is involved in pre-rRNA processing. In a late cytoplasmic processing step, Nob1 cleaves a 20S rRNA intermediate at cleavage site D to produce the mature 18S rRNA (Lamanna and Karbstein, 2009 [PubMed 19706509]).

Target	RNA-Binding Protein NOB1 (NOB1)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC
Host	Mouse
Recommended dilutions	WB: 1/1000 - 1/6000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
Isotype	IgG2a
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by Protein A and Protein G affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	Q9ULX3 (UniProt, ExPASy)
UniProt Secondary AC	Q7L6B7, Q7M4M4, Q7Z4B5, Q9NWB0
UniProt Entry Name	NOB1_HUMAN
Gene Symbol	NOB1
GeneID	28987
OMIM	613586
String	9606.ENSP00000268802
Molecular Weight	Observed MW: 47 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on RNA-Binding Protein NOB1 (NOB1)

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