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Nucleotide-Binding Oligomerization Domain-Containing Protein 1 (NOD1) Antibody
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Catalogue No: abx001158
Price:
US$203.00
(Size: 20 µl)
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NOD1 Antibody is a Rabbit Polyclonal antibody against NOD1. This gene encodes a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid. Multiple alternatively spliced transcript variants differring in the 5' UTR have been described, but the full-length nature of these variants has not been determined.
Research Articles on Nucleotide-Binding Oligomerization Domain-Containing Protein 1 (NOD1)
| Target | Nucleotide-Binding Oligomerization Domain-Containing Protein 1 (NOD1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human NOD1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9Y239 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DTU3, Q549U4, Q8IWF5 |
| UniProt Entry Name | NOD1_HUMAN |
| Gene Symbol | NOD1 |
| GeneID | 10392 |
| NCBI Accession | NP_006083.1 |
| String | 9606.ENSP00000222823 |
| Molecular Weight | Calculated MW: 108 kDa Observed MW: 108 kDa |
| Buffer | PBS, pH 7.3, containing 0.09% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |