Carboxyl-Terminal PDZ Ligand of Neuronal Nitric Oxide Synthase Protein (NOS1AP) Antibody

This gene encodes a cytosolic protein that binds to the signaling molecule, neuronal nitric oxide synthase (nNOS). This protein has a C-terminal PDZ-binding domain that mediates interactions with nNOS and an N-terminal phosphotyrosine binding (PTB) domain that binds to the small monomeric G protein, Dexras1. Studies of the related mouse and rat proteins have shown that this protein functions as an adapter protein linking nNOS to specific targets, such as Dexras1 and the synapsins. Alternative splicing results in multiple transcript variants encoding different isoforms.

Target	Carboxyl-Terminal PDZ Ligand of Neuronal Nitric Oxide Synthase Protein (NOS1AP)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, FCM
Host	Rabbit
Recommended dilutions	WB: 1/1000, FCM: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 437-466 amino acids from the Central region of human NOS1AP.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O75052 (UniProt, ExPASy)
UniProt Secondary AC	B7ZLF5, O43564, Q3T551, Q5VU95
UniProt Entry Name	CAPON_HUMAN
Gene Symbol	NOS1AP
KEGG	hsa:9722
String	9606.ENSP00000355133
Molecular Weight	Calculated MW: 56.2 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse and Rat NOS1AP.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Carboxyl-Terminal PDZ Ligand of Neuronal Nitric Oxide Synthase Protein (NOS1AP)

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