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NAD(P)H Dehydrogenase, Quinone 1 (NQO1) Antibody
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Catalogue No: abx001279
Price:
US$203.00
(Size: 20 µl)
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NQO1 Antibody is a Rabbit Polyclonal antibody against NQO1. This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Research Articles on NAD(P)H Dehydrogenase, Quinone 1 (NQO1)
| Target | NAD(P)H Dehydrogenase, Quinone 1 (NQO1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-274 of human NQO1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P15559 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R5Y9, B4DNM7, B7ZAD1, Q86UK1 |
| Gene Symbol | NQO1 |
| GeneID | 1728 |
| NCBI Accession | NP_000894.1 |
| Molecular Weight | Calculated MW: 31 kDa Observed MW: 31 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |