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Nuclear Receptor Subfamily 1 Group I Member 2 (NR1I2) Antibody
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Catalogue No: abx034057
Price:
US$326.25
(Size: 80 µl)
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NR1I2 belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. This protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin.
Research Articles on Nuclear Receptor Subfamily 1 Group I Member 2 (NR1I2)
| Target | Nuclear Receptor Subfamily 1 Group I Member 2 (NR1I2) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100, IF/ICC: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 100-127 amino acids from the Central region of human NR1I2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O75469 (UniProt, ExPASy) |
| UniProt Entry Name | NR1I2_HUMAN |
| Gene Symbol | NR1I2 |
| KEGG | hsa:8856 |
| String | 9606.ENSP00000336528 |
| Molecular Weight | Calculated MW: 49.8 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |