Photoreceptor Cell Specific Nuclear Receptor / PNR (NR2E3) Antibody

This protein is part of a large family of nuclear receptor transcription factors involved in signaling pathways. Nuclear receptors have been shown to regulate pathways involved in embryonic development, as well as in maintenance of proper cell function in adults. Members of this family are characterized by discrete domains that function in DNA and ligand binding. This gene encodes a retinal nuclear receptor that is a ligand-dependent transcription factor. Defects in this gene are a cause of enhanced S cone syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.

Target	Photoreceptor Cell Specific Nuclear Receptor / PNR (NR2E3)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 170-198 amino acids from the Central region of human NR2E3.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9Y5X4 (UniProt, ExPASy)
UniProt Secondary AC	B6ZGU0, Q9UHM4
UniProt Entry Name	NR2E3_HUMAN
Gene Symbol	NR2E3
String	9606.ENSP00000482504
Molecular Weight	Calculated MW: 44.7 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Cow NR2E3.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Photoreceptor Cell Specific Nuclear Receptor / PNR (NR2E3)

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