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GTPase NRas (NRAS) Antibody
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Catalogue No: abx033657
Price:
US$326.25
(Size: 80 µl)
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NRAS is a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. This protein, which has intrinsic GTPase activity, is activated to a GTP-bound form by a GTPase activating protein and inactivated to a GDP-bound form by a guanine nucleotide-exchange factor. Defects in the gene encoding this protein are a cause of juvenile myelomonocytic leukemia (JMML).
Research Articles on GTPase NRas (NRAS)
| Target | GTPase NRas (NRAS) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 147-179 amino acids from the C-terminal region of human NRAS. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified Rabbit Polyclonal Antibody. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P01111 (UniProt, ExPASy) |
| UniProt Secondary AC | Q14971, Q15104, Q15282 |
| UniProt Entry Name | RASN_HUMAN |
| Gene Symbol | NRAS |
| GeneID | 4893 |
| OMIM | 137550 |
| NCBI Accession | NP_002515.1 |
| HGNC | 7989 |
| KEGG | hsa:4893 |
| Ensembl | ENSG00000213281 |
| String | 9606.ENSP00000358548 |
| Molecular Weight | Calculated MW: 21.2 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Pig NRAS. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |