Nuclear Receptor-Binding Protein (NRBP) Antibody

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Catalogue No: abx033861
Price: US$326.25
(Size: 80 µl)

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Datasheet SDS
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.

Target Nuclear Receptor-Binding Protein (NRBP)
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications ELISA, WB, IHC
Host Rabbit
Recommended dilutions WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 47-76 amino acids from the N-terminal region of human NRBP.
Isotype IgG
Form Liquid
Purification Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q99J45 (UniProt, ExPASy)
UniProt Secondary AC Q8BL77
UniProt Entry Name NRBP_MOUSE
KEGG mmu:192292
String 10090.ENSMUSP00000031034
Molecular Weight Calculated MW: 59.9 kDa
Buffer PBS containing 0.09% sodium azide.
Specificity Predicted to react with Monkey Nrbp1.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Nuclear Receptor-Binding Protein (NRBP)


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