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Neurotrophic Tyrosine Kinase Receptor Type 3 (NTRK3) Antibody
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Catalogue No: abx012016
Price:
US$420.50
(Size: 100 µl)
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This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers.
Research Articles on Neurotrophic Tyrosine Kinase Receptor Type 3 (NTRK3)
| Target | Neurotrophic Tyrosine Kinase Receptor Type 3 (NTRK3) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, IHC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant extracellular fragment of human NTRK3 (32-429 AA) fused with hIgGFc tag expressed in HEK293 cells. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q16288 (UniProt, ExPASy) |
| UniProt Secondary AC | B7Z4C5, E9PG56, H0YND1, O75682, Q12827, Q16289 |
| UniProt Entry Name | NTRK3_HUMAN |
| Gene Symbol | NTRK3 |
| GeneID | 4916 |
| OMIM | 191316 |
| HGNC | 8033 |
| KEGG | hsa:4916 |
| Ensembl | ENSG00000140538 |
| String | 9606.ENSP00000354207 |
| Enzyme Commission Number | EC 2.7.10.1 |
| Molecular Weight | 94 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |