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Nucleoporin 50 (NUP50) Antibody
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Catalogue No: abx025091
Price:
US$326.25
(Size: 80 µl)
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The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. NUP50 is a member of the FG-repeat containing nucleoporins that functions as a soluble cofactor in importin-alpha:beta-mediated nuclear protein import. NUP50 may serve as a binding site on the nuclear side of the pore complex for export receptor-cargo complexes. It interacts with multiple transport receptor proteins including p27Kip1. This interaction is required for correct intracellular transport and degradation of p27Kip1.
Research Articles on Nucleoporin 50 (NUP50)
| Target | Nucleoporin 50 (NUP50) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 432-461 amino acids from the C-terminal region of human NUP50. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified Rabbit Polyclonal Antibody. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9UKX7 (UniProt, ExPASy) |
| UniProt Secondary AC | B1AHA4, B2RB15, O75644, Q8N6V5, Q9NPM9, Q9NPR6, Q9P1K5 |
| UniProt Entry Name | NUP50_HUMAN |
| String | 9606.ENSP00000345895 |
| Molecular Weight | Calculated MW: 50.1 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Rat NUP50. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |