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Nucleoporin 98 (NUP98) Antibody
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Catalogue No: abx000745
Price:
US$203.00
(Size: 20 µl)
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NUP98 Antibody is a Rabbit Polyclonal antibody against NUP98. Nup98-Nup96 (also known as Nup196, ADIR2 or ADAR2), encoded by NUP98 gene, is a component of the nuclear pore complex (NPC) protein first synthesized as 186-198 kDa Nup98-Nup96 precursors and the precursors shortly undergo autoproteolysis to give rise to two nucleoporins, the amino-terminal Nup98 (Nup98-N) and carboxy-terminal Nup96 (Nup96-C). Both of Nup98 and Nup96 are localized to the nucleoplasmic side of the NPC. This antibody was raised against the carboxy-terminal region of Nup98-Nup96, it recognizes all Nup98-Nup96 proteins except Nup98-N. Since the autoproteolysis is very rapid this antibody usually detected 98-115 kDa Nup96 protein in multiple cell lines protein notable that RNA-editing deaminase 1 (Gene ID: 104), also named ADAR2, is a different Nup98-Nup96 (ADAR2).
Research Articles on Nucleoporin 98 (NUP98)
| Target | Nucleoporin 98 (NUP98) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 621-920 of human NUP98. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P52948 (UniProt, ExPASy) |
| UniProt Entry Name | NUP98_HUMAN |
| Gene Symbol | NUP98 |
| GeneID | 4928 |
| NCBI Accession | NP_624357.1 |
| KEGG | hsa:4928 |
| String | 9606.ENSP00000316032 |
| Molecular Weight | Calculated MW: 198 kDa Observed MW: 105 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |