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Ornithine Aminotransferase, Mitochondrial (OAT) Antibody
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Catalogue No: abx004761
Price:
US$217.50
(Size: 20 µl)
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OAT Antibody is a Rabbit Polyclonal antibody against OAT. This gene encodes the mitochondrial enzyme ornithine aminotransferase, which is a key enzyme in the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Mutations that result in a deficiency of this enzyme cause the autosomal recessive eye disease Gyrate Atrophy. Alternatively spliced transcript variants encoding different isoforms have been described. Related pseudogenes have been defined on the X chromosome.
Research Articles on Ornithine Aminotransferase, Mitochondrial (OAT)
| Target | Ornithine Aminotransferase, Mitochondrial (OAT) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC, IP |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200, IP: 0.5 µg - 4 µg antibody per 200 µg - 400 µg extracts of whole cells. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 160-439 of human OAT. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P04181 (UniProt, ExPASy) |
| UniProt Secondary AC | D3DRF0, Q16068, Q16069, Q68CS0, Q6IAV9, Q9UD03 |
| UniProt Entry Name | OAT_HUMAN |
| Gene Symbol | OAT |
| GeneID | 4942 |
| NCBI Accession | NP_000265.1 |
| KEGG | hsa:4942 |
| String | 9606.ENSP00000357838 |
| Molecular Weight | Calculated MW: 49 kDa Observed MW: 49 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |