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POU Class 5 Homeobox 1 / OCT4 (POU5F1) Antibody
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Catalogue No: abx016070
Price:
US$427.75
(Size: 100 µl)
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This gene encodes a transcription factor containing a POU homeodomain.This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency.A translocation of this gene with the Ewing's sarcoma gene, t (6;22) (p21;q12), has been linked to tumor formation.Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon.Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. (provided by RefSeq).Tissue specificity: Expressed in developing brain.Highest levels found in specific cell layers of the cortex, the olfactory bulb, the hippocampus and the cerebellum.Low levels of expression in adult tissues.
Research Articles on POU Class 5 Homeobox 1 / OCT4 (POU5F1)
| Target | POU Class 5 Homeobox 1 / OCT4 (POU5F1) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Synthesized peptide of human Oct4. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q01860 (UniProt, ExPASy) |
| UniProt Entry Name | PO5F1_HUMAN |
| Gene Symbol | POU5F1 |
| GeneID | 5460 |
| OMIM | 164177 |
| HGNC | 9221 |
| KEGG | hsa:5460 |
| Ensembl | ENSG00000204531 |
| String | 9606.ENSP00000259915 |
| Molecular Weight | 45 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |