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Oxoglutarate Dehydrogenase (OGDH) Antibody
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Catalogue No: abx027396
Price:
US$290.00
(Size: 80 µl)
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This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO (2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Research Articles on Oxoglutarate Dehydrogenase (OGDH)
| Target | Oxoglutarate Dehydrogenase (OGDH) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 381-410 amino acids from the C-terminal region of human OGDH. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q02218 (UniProt, ExPASy) |
| UniProt Secondary AC | B4E2U9, D3DVL0, E9PBM1, Q96DD3, Q9UDX0 |
| UniProt Entry Name | ODO1_HUMAN |
| KEGG | hsa:4967 |
| String | 9606.ENSP00000222673 |
| Molecular Weight | Calculated MW: 116 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |