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Mu-Type Opioid Receptor (OPRM1) Antibody
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Catalogue No: abx034237
Price:
US$290.00
(Size: 80 µl)
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OPRM1 is the mu opioid receptor, which is the primary site of action for the most commonly used opioids, including morphine, heroin, fentanyl, and methadone. It is also the primary receptor for endogenous opioid peptides beta-endorphin (see POMC, MIM 176830) and the enkephalins (see PENK, MIM 131330). The OPRM1 receptor is a membrane of the G protein-coupled receptor family (Bond et al., 1998 [PubMed 9689128]). There are at least 3 types of opioid receptors, mu, kappa (OPRK1; MIM 165196), and delta, each with a distinct pharmacologic profile.
Research Articles on Mu-Type Opioid Receptor (OPRM1)
| Target | Mu-Type Opioid Receptor (OPRM1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 161-187 amino acids from the Central region of human OPRM1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P35372 (UniProt, ExPASy) |
| UniProt Entry Name | OPRM_HUMAN |
| Gene Symbol | OPRM1 |
| GeneID | 4988 |
| KEGG | hsa:4988 |
| String | 9606.ENSP00000394624 |
| Molecular Weight | Calculated MW: 44.8 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Rat, Pig and Monkey OPRM1. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |