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Calcium Release-Activated Calcium Channel Protein 1 (ORAI1) Antibody
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Catalogue No: abx005529
Price:
US$348.00
(Size: 60 µl)
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ORAI1 Antibody is a Rabbit Polyclonal antibody against ORAI1. The protein encoded by this gene is a membrane calcium channel subunit that is activated by the calcium sensor STIM1 when calcium stores are depleted. This type of channel is the primary way for calcium influx into T-cells. Defects in this gene are a cause of immune dysfunction with T-cell inactivation due to calcium entry defect type 1 (IDTICED1).
Research Articles on Calcium Release-Activated Calcium Channel Protein 1 (ORAI1)
| Target | Calcium Release-Activated Calcium Channel Protein 1 (ORAI1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/200 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic peptide corresponding to human ORAI1 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q96D31 (UniProt, ExPASy) |
| UniProt Secondary AC | Q3MHV3, Q6DHX2, Q96BP7, Q96K71 |
| UniProt Entry Name | CRCM1_HUMAN |
| Gene Symbol | ORAI1 |
| GeneID | 84876 |
| OMIM | 610277 |
| NCBI Accession | NP_116179.2 NM_032790.3 |
| HGNC | 25896 |
| KEGG | hsa:84876 |
| Ensembl | ENSG00000276045 |
| String | 9606.ENSP00000480616 |
| Molecular Weight | Calculated MW: 25 kDa/32 kDa Observed MW: 32-55 kDa |
| Buffer | PBS, pH 7.3, containing 0.01% thiomersal, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
