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Origin Recognition Complex Subunit 6 (ORC6) Antibody
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Catalogue No: abx004156
Price:
US$203.00
(Size: 20 µl)
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ORC6 Antibody is a Rabbit Polyclonal antibody against ORC6. The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis.
Research Articles on Origin Recognition Complex Subunit 6 (ORC6)
| Target | Origin Recognition Complex Subunit 6 (ORC6) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-252 of human ORC6. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9Y5N6 (UniProt, ExPASy) |
| UniProt Secondary AC | B3KN89 |
| UniProt Entry Name | ORC6_HUMAN |
| Gene Symbol | ORC6 |
| GeneID | 23594 |
| NCBI Accession | NP_055136.1 |
| String | 9606.ENSP00000219097 |
| Molecular Weight | Calculated MW: 28 kDa Observed MW: 28 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |