+44 (0) 1223 755950
+1 832 327 7413
Osteoclast Associated Receptor (OSCAR) Antibody
REQUEST MORE INFO
Catalogue No: abx030601
Price:
US$326.25
(Size: 80 µl)
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex (LRC) protein family that plays critical roles in the regulation of both innate and adaptive immune responses. Different from the other LRC members, OSCAR expression is detected specifically in preosteoclasts or mature osteoclasts. OSCAR may be an important bone-specific regulator of osteoclast differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Research Articles on Osteoclast Associated Receptor (OSCAR)
| Target | Osteoclast Associated Receptor (OSCAR) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 205-231 amino acids from the C-terminal region of human OSCAR. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q8IYS5 (UniProt, ExPASy) |
| UniProt Secondary AC | B7WNS2, Q5GRG5, Q8N763, Q8NHL4, Q8WXQ0, Q8WXQ1, Q8WXQ2 |
| UniProt Entry Name | OSCAR_HUMAN |
| Gene Symbol | OSCAR |
| KEGG | hsa:126014 |
| String | 9606.ENSP00000479089 |
| Molecular Weight | Calculated MW: 30.5 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |