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Homeobox Protein OTX2 (OTX2) Antibody
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Catalogue No: abx004195
Price:
US$203.00
(Size: 20 µl)
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OTX2 Antibody is a Rabbit Polyclonal antibody against OTX2. This gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6). This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine.
Research Articles on Homeobox Protein OTX2 (OTX2)
| Target | Homeobox Protein OTX2 (OTX2) |
| Clonality | Polyclonal |
| Reactivity | Mouse |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 140-280 of human OTX2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P32243 (UniProt, ExPASy) |
| UniProt Secondary AC | B2RAN5, Q6GTV3, Q9HAW3, Q9P2R1 |
| UniProt Entry Name | OTX2_HUMAN |
| Gene Symbol | OTX2 |
| GeneID | 5015 |
| NCBI Accession | NP_068374.1 |
| KEGG | hsa:5015 |
| String | 9606.ENSP00000343819 |
| Molecular Weight | Calculated MW: 32 kDa Observed MW: 32 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |