ATP-Dependent Translocase ABCB1 (ABCB1) Antibody

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Catalogue No: abx149070
Price: US$406.00
(Size: 100 µg)

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Datasheet SDS
ATP-Dependent Translocase ABCB1 (ABCB1) Antibody is a Rabbit Polyclonal antibody for the detection of P Glycoprotein.

ABCB1 (also known as P-gp/ P-glycoprotein, MDR1/multidrug-resistance 1) is a plasma membrane protein first discovered in multidrug resistant tumor cells. ABCB1 can extrude a large number of medically relevant compounds from cells and causes drug resistance. ABCB1 is expressed in a variety of human cancers as well as normal tissues including brain, and placenta. Overexpression of ABCB1 correlates with a negative prognosis in several types of cancer.

Target ATP-Dependent Translocase ABCB1 (ABCB1)
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications ELISA, WB, IHC, IP
Host Rabbit
Recommended dilutions WB: 1/200 - 1/1000, IHC: 1/50 - 1/500, IP: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen ABCB1
Isotype IgG
Form Liquid
Purity ≥ 95% (SDS-PAGE)
Purification Purified by immunogen affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity 12 months.
UniProt Primary AC P08183 (UniProt, ExPASy)
UniProt Secondary AC A8K294, B5AK60, Q12755, Q14812
UniProt Entry Name MDR1_HUMAN
Gene Symbol ABCB1
GeneID 5243
OMIM 171050
HGNC 40
KEGG hsa:5243
Ensembl ENSG00000085563
String 9606.ENSP00000478255
Molecular Weight Observed MW: 142 kDa
Buffer PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration 2 mg/ml
Availability Shipped within 5-12 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on ATP-Dependent Translocase ABCB1 (ABCB1)


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