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Cyclin-Dependent Kinase 4 Inhibitor D (CDKN2D) Antibody
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Catalogue No: abx034359
Price:
US$326.25
(Size: 80 µl)
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p19 is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis.
Research Articles on Cyclin-Dependent Kinase 4 Inhibitor D (CDKN2D)
| Target | Cyclin-Dependent Kinase 4 Inhibitor D (CDKN2D) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/2000, IHC-P: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 15-43 amino acids from the N-terminal region of human p19. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P55273 (UniProt, ExPASy) |
| UniProt Secondary AC | Q13102, Q6FGE9 |
| UniProt Entry Name | CDN2D_HUMAN |
| NCBI Accession | NP_001791.1 NP_524145.1 |
| KEGG | hsa:1032 |
| String | 9606.ENSP00000377224 |
| Molecular Weight | Calculated MW: 17.7 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |