p27Kip1 Antibody

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Catalogue No: abx031336
Price: US$326.25
(Size: 80 µl)

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p27Kip1 Antibody
p27Kip1 Antibody

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Datasheet SDS
This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. [provided by RefSeq].

Target p27Kip1
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications ELISA, WB
Host Rabbit
Recommended dilutions WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human p27Kip1.
Isotype IgG
Form Liquid
Purification Purified through a protein A column, followed by peptide affinity purification.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P46527 (UniProt, ExPASy)
UniProt Secondary AC Q16307, Q5U0H2, Q9BUS6
UniProt Entry Name CDN1B_HUMAN
NCBI Accession NP_004055.1
KEGG hsa:1027
String 9606.ENSP00000228872
Molecular Weight Calculated MW: 22.1 kDa
Buffer PBS containing 0.09% sodium azide.
Specificity Predicted to react with Hamster CDKN1B.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on p27Kip1
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