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Purinergic Receptor P2X 1 (P2RX1) Antibody
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Catalogue No: abx029072
Price:
US$326.25
(Size: 80 µl)
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The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle, being responsible, for example, for sympathetic vasoconstriction in small arteries, arterioles and vas deferens. Mouse studies suggest that this receptor is essential for normal male reproductive function. It is possible that the development of selective antagonists for this receptor may provide an effective non-hormonal male contraceptive pill.
Research Articles on Purinergic Receptor P2X 1 (P2RX1)
| Target | Purinergic Receptor P2X 1 (P2RX1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 345-372 amino acids from the C-terminal region of human P2RX1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P51575 (UniProt, ExPASy) |
| UniProt Secondary AC | Q9UK84 |
| UniProt Entry Name | P2RX1_HUMAN |
| KEGG | hsa:5023 |
| String | 9606.ENSP00000225538 |
| Molecular Weight | Calculated MW: 45 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse and Rat P2RX1. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |