Purinergic Receptor P2X 1 (P2RX1) Antibody

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle, being responsible, for example, for sympathetic vasoconstriction in small arteries, arterioles and vas deferens. Mouse studies suggest that this receptor is essential for normal male reproductive function. It is possible that the development of selective antagonists for this receptor may provide an effective non-hormonal male contraceptive pill.

Target	Purinergic Receptor P2X 1 (P2RX1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 345-372 amino acids from the C-terminal region of human P2RX1.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P51575 (UniProt, ExPASy)
UniProt Secondary AC	Q9UK84
UniProt Entry Name	P2RX1_HUMAN
KEGG	hsa:5023
String	9606.ENSP00000225538
Molecular Weight	Calculated MW: 45 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse and Rat P2RX1.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Purinergic Receptor P2X 1 (P2RX1)

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