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Mitogen-Activated Protein Kinase 14 Phospho-Tyr322 (MAPK14 pY322) Cell ELISA Kit
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Catalogue No: abx596022
Price:
US$609.00
(Size: 2 × 96 tests)
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p38 MAPK (pY322) Cell ELISA Kit is a cell-based ELISA Kit. Cells to be assayed should be seeded onto a clear flat bottom 96 well plate, using poly-L-lysine for non-adherent cells. Cells should be grown to 75-90% confluence and treated prior to carrying out the ELISA.
Research Articles on Mitogen-Activated Protein Kinase 14 Phospho-Tyr322 (MAPK14 pY322)
| Introduction | p38 Mitogen Activated Protein Kinases (p38 MAPK) are a group of enzymes involved in cell survival / apoptosis in response to stresses, such as heat shock, UV exposure, and cytokines. In humans, the p38 MAPK family consists of MAPK11 (p38-β), MAPK12 (p38-γ), MAPK13 (p38-δ), and MAPK14 (p38-α). These proteins are activated by MAP2K3, which phosphorylates them. Aberrant activation of p38 MAPKs is associated with cancer and immune dysregulation. |
| Target | Mitogen-Activated Protein Kinase 14 Phospho-Tyr322 (MAPK14 pY322) |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA |
| Recommended dilutions | Optimal dilutions/concentrations should be determined by the end user. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Validity | 6 months. |
| UniProt Primary AC | Q16539 (UniProt, ExPASy) |
| UniProt Entry Name | MK14_HUMAN |
| Gene Symbol | MAPK14 |
| GeneID | 1432 |
| OMIM | 600289 |
| HGNC | 6876 |
| KEGG | hsa:1432 |
| Ensembl | ENSG00000112062 |
| String | 9606.ENSP00000229795 |
| Detection Method | Fluorometric |
| Plate Coating | Uncoated |
| Substrate | TMB |
| Detection Antibody Conjugation | HRP |
| Availability | Shipped within 1-2 weeks. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |