Prolyl 4-Hydroxylase Subunit Alpha-1 (P4HA1) Antibody

This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described.

Target	Prolyl 4-Hydroxylase Subunit Alpha-1 (P4HA1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 414-442 amino acids from the C-terminal region of human P4HA1.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P13674 (UniProt, ExPASy)
UniProt Secondary AC	C9JL12, Q15082, Q15083, Q5VSQ5
UniProt Entry Name	P4HA1_HUMAN
KEGG	hsa:5033
String	9606.ENSP00000263556
Molecular Weight	Calculated MW: 61 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Cow P4HA1.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Prolyl 4-Hydroxylase Subunit Alpha-1 (P4HA1)

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