Cellular Tumor Antigen P53 (TP53) Cell ELISA Kit

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Catalogue No: abx595447
Price: US$572.75
(Size: 96 tests)
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Cellular Tumor Antigen P53 (TP53) Cell ELISA Kit

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Datasheet SDS Download Manual
p53 Cell ELISA Kit is a cell-based ELISA Kit. Cells to be assayed should be seeded onto a clear flat bottom 96 well plate, using poly-L-lysine for non-adherent cells. Cells should be grown to 75-90% confluence and treated prior to carrying out the ELISA.

Introduction Tumor Antigen P53 (TP53), also known as p53, is a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome.
Target Cellular Tumor Antigen P53 (TP53)
Reactivity Human, Mouse, Rat
Tested Applications ELISA
Recommended dilutions Optimal dilutions/concentrations should be determined by the end user.
Storage Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Validity 6 months.
UniProt Primary AC P04637 (UniProt, ExPASy)
UniProt Entry Name P53_HUMAN
Gene Symbol TP53
GeneID 7157
OMIM 133239
HGNC 11998
KEGG hsa:7157
Ensembl ENSG00000141510
String 9606.ENSP00000269305
Detection Method Colorimetric
Plate Coating Uncoated
Substrate TMB
Detection Antibody Conjugation HRP
Availability Shipped within 1-2 weeks.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES.

Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
Research Articles on Cellular Tumor Antigen P53 (TP53)
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