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Proteasomal ATPase-Associated Factor 1 (PAAF1) Antibody
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Catalogue No: abx032396
Price:
US$326.25
(Size: 80 µl)
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PAAF1 inhibits proteasome 26S assembly and proteolytic activity by impairing the association of the 19S regulatory complex with the 20S core. In case of HIV-1 infection, recruited by viral Tat to the HIV-1 promoter, where it promotes the recruitment of 19S regulatory complex through dissociation of the proteasome 26S. This presumably promotes provirus transcription efficiency.
Research Articles on Proteasomal ATPase-Associated Factor 1 (PAAF1)
| Target | Proteasomal ATPase-Associated Factor 1 (PAAF1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 109-138 amino acids from the N-terminal region of human PAAF1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9BRP4 (UniProt, ExPASy) |
| UniProt Entry Name | PAAF1_HUMAN |
| Gene Symbol | PAAF1 |
| String | 9606.ENSP00000311665 |
| Molecular Weight | Calculated MW: 42.2 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Cow PAAF1. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |