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Parkin Coregulated Gene Protein (PACRG) Antibody
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Catalogue No: abx029689
Price:
US$326.25
(Size: 80 µl)
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This gene encodes a protein that is conserved across metazoans. In vertebrates, this gene is linked in a head-to-head arrangement with the adjacent parkin gene, which is associated with autosomal recessive juvenile Parkinson's disease. These genes are co-regulated in various tissues and they share a bi-directional promoter. Both genes are associated with susceptibility to leprosy. The parkin co-regulated gene protein forms a large molecular complex with chaperones, including heat shock proteins 70 and 90, and chaperonin components. This protein is also a component of Lewy bodies in Parkinson's disease patients, and it suppresses unfolded Pael receptor-induced neuronal cell death. Multiple transcript variants encoding different isoforms have been found for this gene.
Research Articles on Parkin Coregulated Gene Protein (PACRG)
| Target | Parkin Coregulated Gene Protein (PACRG) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 46-74 amino acids from the N-terminal region of human PACRG. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q96M98 (UniProt, ExPASy) |
| UniProt Secondary AC | E1P5B5, Q6IMB8, Q8IZM1, Q8NHP5, Q9H1V9 |
| UniProt Entry Name | PACRG_HUMAN |
| Gene Symbol | PACRG |
| KEGG | hsa:135138 |
| String | 9606.ENSP00000337946 |
| Molecular Weight | Calculated MW: 33.3 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |