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PAK1 (pT212) Antibody
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Catalogue No: abx031946
Price:
US$326.25
(Size: 80 µl)
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PAK proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. These proteins serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK1 regulates cell motility and morphology.
Research Articles on PAK1 (pT212)
| Target | PAK1 (pT212) |
| Clonality | Polyclonal |
| Target Modification | Thr212 |
| Modification | Phosphorylation |
| Reactivity | Human |
| Tested Applications | ELISA, DB |
| Host | Rabbit |
| Recommended dilutions | DB: 1/500. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T212 of human PAK1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by protein A affinity chromatography. Then, the antibody fraction was peptide affinity purified in a 2-step procedure with peptides. The antibody was eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q13153 (UniProt, ExPASy) |
| UniProt Secondary AC | O75561, Q13567, Q32M53, Q32M54, Q86W79 |
| UniProt Entry Name | PAK1_HUMAN |
| KEGG | hsa:5058 |
| String | 9606.ENSP00000278568 |
| Molecular Weight | Calculated MW: 60.6 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse and Rat PAK1. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |