P21 Protein Activated Kinase 2 (PAK2) Antibody

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Catalogue No: abx033767
Price: US$326.25
(Size: 80 µl)

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P21 Protein Activated Kinase 2 (PAK2) Antibody P21 Protein Activated Kinase 2 (PAK2) Antibody

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Datasheet SDS
PAK2, a member of the STE20 subfamily of Ser/Thr protein kinases, acts on a variety of targets. It phosphorylates ribosomal protein S6, histone H4 and myelin basic protein. PAK2 interacts tightly with GTP-bound but not GDP-bound CDC42/p21 and RAC1. Expression is ubiquitous, with higher levels seen in skeletal muscle, ovary, thymus and spleen. PAK2 is autophosphorylated when activated by CDC42/p21. The protein structure contains 1 CRIB domain.

Target P21 Protein Activated Kinase 2 (PAK2)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA, WB, IHC
Host Rabbit
Recommended dilutions WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 192-222 amino acids from the N-terminal region of human PAK2.
Isotype IgG
Form Liquid
Purification Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q13177 (UniProt, ExPASy)
UniProt Secondary AC Q13154, Q6ISC3
UniProt Entry Name PAK2_HUMAN
KEGG hsa:5062
String 9606.ENSP00000314067
Molecular Weight Calculated MW: 58 kDa
Buffer PBS containing 0.09% sodium azide.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on P21 Protein Activated Kinase 2 (PAK2)
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