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Serine/Threonine-Protein Kinase PAK 4 (PAK4) Antibody
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Catalogue No: abx033769
Price:
US$290.00
(Size: 80 µl)
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PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3, PAK4, PAK5, and PAK6. PAK proteins serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton.
Research Articles on Serine/Threonine-Protein Kinase PAK 4 (PAK4)
| Target | Serine/Threonine-Protein Kinase PAK 4 (PAK4) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 156-187 amino acids from the N-terminal region of human PAK4. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by saturated ammonium sulfate (SAS) precipitation followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O96013 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DGG6, Q8N4E1, Q8NCH5, Q8NDE3, Q9BU33, Q9ULS8 |
| UniProt Entry Name | PAK4_HUMAN |
| Gene Symbol | PAK4 |
| GeneID | 10298 |
| KEGG | hsa:10298 |
| String | 9606.ENSP00000469413 |
| Molecular Weight | Calculated MW: 64.1 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |