Serine/Threonine-Protein Kinase PAK 5 (PAK5) Antibody

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Catalogue No: abx033770
Price: US$326.25
(Size: 80 µl)

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Datasheet SDS
PAK5 is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression.

Target Serine/Threonine-Protein Kinase PAK 5 (PAK5)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA, WB, IHC
Host Rabbit
Recommended dilutions WB: 1/2000, IHC-P: 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 168-198 amino acids from human PAK5.
Isotype IgG
Form Liquid
Purification Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q9P286 (UniProt, ExPASy)
UniProt Secondary AC A8K5T6, D3DW14, Q5W115, Q8TB93, Q9BX09, Q9ULF6
UniProt Entry Name PAK5_HUMAN
String 9606.ENSP00000367686
Molecular Weight Calculated MW: 80.7 kDa
Buffer PBS containing 0.09% sodium azide.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Serine/Threonine-Protein Kinase PAK 5 (PAK5)


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