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E. coli Pantothenate Kinase (COAA) Protein
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Catalogue No: abx073459
Price:
US$261.00
(Size: 5 µg)
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Pantothenate Kinase Protein is a recombinant protein kinase. COAA is a member of the prokaryotic pantothenate kinase family and it is the first enzyme in the Coenzyme A biosynthetic pathway. COAA phosphorylates pantothenate (vitamin B5) to form 4'-phosphopantothenate. The key factor controlling the intracellular CoA concentration is the regulation of COAA activity by feedback inhibition.
Research Articles on Pantothenate Kinase (COAA)
| Target | Pantothenate Kinase (COAA) |
| Origin | E. coli |
| Expression | Recombinant |
| Tested Applications | SDS-PAGE |
| Host | E. coli |
| Recommended dilutions | Optimal dilutions/concentrations should be determined by the end user. |
| Form | Liquid |
| Purity | > 95% (SDS-PAGE) |
| Purification | Purified by proprietary chromatographic techniques. |
| Storage | Store at 4 °C if entire vial will be used within 2-4 weeks. Store at -20 °C for long-term storage. For long-term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P0A6I3 (UniProt, ExPASy) |
| UniProt Secondary AC | P15044, Q2M8R5 |
| UniProt Entry Name | COAA_ECOLI |
| KEGG | ecj:JW3942 eco:b3974 |
| String | 511145.b3974 |
| Molecular Weight | 38.9 kDa |
| Sequence Fragment | 1-316 AA |
| Sequence | MGSSHHHHHH SSGLVPRGSH MGSHMSIKEQ TLMTPYLQFD RNQWAALRDS VPMTLSEDEI ARLKGINEDL SLEEVAEIYL PLSRLLNFYI SSNLRRQAVL EQFLGTNGQR IPYIISIAGS VAVGKSTTAR VLQALLSRWP EHRRVELITT DGFLHPNQVL KERGLMKKKG FPESYDMHRL VKFVSDLKSG VPNVTAPVYS HLIYDVIPDG DKTVVQPDIL ILEGLNVLQS GMDYPHDPHH VFVSDFVDFS IYVDAPEDLL QTWYINRFLK FREGAFTDPD SYFHNYAKLT KEEAIKTAMT LWKEINWLNL KQNILPTRER ASLILTKSAN HAVEEVRLRK. |
| Tag | N-terminal His tag |
| Buffer | 20 mM Tris-HCl (pH 8.0), 200 mM NaCl, 2 mM DTT and 10% glycerol. |
| Activity | Not tested |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |