Protease Activated Receptor 4 (PAR4) Antibody

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Catalogue No: abx016047
Price: US$427.75
(Size: 100 µl)
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Western blot analysis using PAR4 antibody against full-length Trx-Par4 recombinant protein (1) and Hela cell lysate (2).
Protease Activated Receptor 4 (PAR4) Antibody Protease Activated Receptor 4 (PAR4) Antibody Protease Activated Receptor 4 (PAR4) Antibody

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Datasheet SDS
Prostate apoptosis response 4 (Par4) is a 38kD protein originally identified as the product of a gene that is upregulated in prostate tumor cells undergoing apoptosis.It is a leucine zipper and death domain containing protein whose levels increase in neurons undergoing apoptosis as a result of trophic factor withdrawal or exposure to oxidative and metabolic insults.Par4 levels are reported to be increased in their lumbar spinal cord specimens further suggesting a role in neuronal degeneration.The tumor suppressor WT1 represses and activates transcription.The loss and/or imbalance of the dual transcriptional activity of WT1 may contribute to Wilms tumor.Par4 is a WT1 interacting protein that also functions as a transcriptional repressor.

Target Protease Activated Receptor 4 (PAR4)
Clonality Monoclonal
Reactivity Human
Tested Applications ELISA, WB, IHC
Host Mouse
Recommended dilutions ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Purified recombinant fragment of PAR4 (aa1-330) expressed in E. coli.
Isotype IgG1
Form Liquid
Purification Unpurified ascites.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q96IZ0 (UniProt, ExPASy)
UniProt Secondary AC O75796, Q6FHY9, Q8N700
UniProt Entry Name PAWR_HUMAN
Gene Symbol PAWR
GeneID 5074
OMIM 601936
HGNC 8614
KEGG hsa:5074
Ensembl ENSG00000177425
String 9606.ENSP00000328088
Buffer Ascitic fluid containing 0.03% sodium azide.
Concentration Not determined.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Protease Activated Receptor 4 (PAR4)
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